CACNB2, calcium voltage-gated channel auxiliary subunit beta 2

CACNB2, calcium voltage-gated channel auxiliary subunit beta 2

• This gene encodes a subunit of a voltage-dependent calcium channel protein that is a member of the voltage-gated calcium channel superfamily. The gene product was originally identified as an antigen target in Lambert-Eaton myasthenic syndrome, an autoimmune disorder. Mutations in this gene are associated with Brugada syndrome. Alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Feb 2013]

• Gene Synonyms (voltage-dependent L-type calcium channel subunit beta-2, calcium channel voltage-dependent subunit beta 2, calcium channel, voltage-dependent, beta 2 subunit, lambert-Eaton myasthenic syndrome antigen B, myasthenic (Lambert-Eaton) syndrome antigen B, CAB2, CACNLB2, CAVB2, MYSB,)
• NCBI Gene ID: 783
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q59H42
  UNIPROT ID#>>Q5VVH1
  UNIPROT ID#>>Q08289
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

calcium voltage-gated channel auxiliary subunit beta 2 interacts with:

• anterior gradient 2, protein disulphide isomerase family member
  calcium voltage-gated channel auxiliary subunit beta 3
  C-terminal binding protein 2
  heterogeneous nuclear ribonucleoprotein L
  HEXIM P-TEFb complex subunit 2
  protein arginine methyltransferase 5
  protein kinase cAMP-activated catalytic subunit alpha
  RRAD and GEM like GTPase 1
  transmembrane protein 174

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.