CA2, carbonic anhydrase 2

CA2, carbonic anhydrase 2

• The protein encoded by this gene is one of several isozymes of carbonic anhydrase, which catalyzes reversible hydration of carbon dioxide. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]

• Gene Synonyms (carbonic anhydrase 2, carbonate dehydratase II, carbonic anhydrase B, carbonic anhydrase C, carbonic anhydrase II, carbonic dehydratase, epididymis luminal protein 76, epididymis secretory protein Li 282, CA-II, CAC, CAII, Car2, HEL-76, HEL-S-282,)
• NCBI Gene ID: 760
• Species: Homo sapiens (Human)
• UNIPROT ID#>>V9HW21
  UNIPROT ID#>>P00918
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

carbonic anhydrase 2 interacts with:

• acyl-CoA thioesterase 1
  ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1
  anterior gradient 2, protein disulphide isomerase family member
  carbonic anhydrase 9
  cullin 1
  cullin 4A
  cyclin-dependent kinase 1
  dispatched RND transporter family member 3
  dynein light chain LC8-type 1
  EWS RNA binding protein 1
  FUS RNA binding protein
  heat shock protein family D (Hsp60) member 1
  HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
  leucine rich repeat kinase 2
  non-POU domain containing octamer binding
  nuclear receptor subfamily 2 group C member 2
  proliferating cell nuclear antigen
  PTEN induced kinase 1
  regulatory associated protein of MTOR complex 1
  ring finger protein 4
  solute carrier family 4 member 1 (Diego blood group)
  solute carrier family 4 member 2
  solute carrier family 4 member 3
  solute carrier family 4 member 4
  solute carrier family 4 member 8
  solute carrier family 9 member A1
  ubiquitin conjugating enzyme E2 M
  ubiquitin specific peptidase 42

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.