ZFP36L1, ZFP36 ring finger protein like 1

ZFP36L1, ZFP36 ring finger protein like 1

• This gene is a member of the TIS11 family of early response genes, which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. This gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

• Gene Synonyms (mRNA decay activator protein ZFP36L1, EGF-response factor 1, TPA-induced sequence 11b, ZFP36-like 1, butyrate response factor 1, early response factor Berg36, zinc finger protein 36, C3H type-like 1, zinc finger protein 36, C3H1 type-like 1, zinc finger protein, C3H type, 36-like 1, BRF1, Berg36, ERF-1, ERF1, RNF162B, TIS11B, cMG1,)
• NCBI Gene ID: 677
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B3KNA8
  UNIPROT ID#>>Q07352
  UNIPROT ID#>>A0A024R658
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ZFP36 ring finger protein like 1 interacts with:

• ACD shelterin complex subunit and telomerase recruitment factor
  CCR4-NOT transcription complex subunit 6
  decapping mRNA 2
  egl-9 family hypoxia inducible factor 3
  ELAV like RNA binding protein 1
  exosome component 2
  exportin 1
  hypoxia inducible factor 1 subunit alpha inhibitor
  MAPK activated protein kinase 2
  mitogen-activated protein kinase 14
  platelet activating factor acetylhydrolase 1b catalytic subunit 2
  protection of telomeres 1
  RNA binding motif protein 8A
  telomeric repeat binding factor 1
  TERF1 interacting nuclear factor 2
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.