CCL17, C-C motif chemokine ligand 17

CCL17, C-C motif chemokine ligand 17

• This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. [provided by RefSeq, Sep 2014]

• Gene Synonyms (C-C motif chemokine 17, CC chemokine TARC, T cell-directed CC chemokine, chemokine (C-C motif) ligand 17, small inducible cytokine subfamily A (Cys-Cys), member 17, small-inducible cytokine A17, thymus and activation-regulated chemokine, A-152E5.3, ABCD-2, SCYA17, TARC,)
• NCBI Gene ID: 6361
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q92583
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

C-C motif chemokine ligand 17 interacts with:

• C-C motif chemokine ligand 17
  vascular cell adhesion molecule 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.