AVPR1B, arginine vasopressin receptor 1B

AVPR1B, arginine vasopressin receptor 1B

• The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq, Jul 2008]

• Gene Synonyms (vasopressin V1b receptor, AVPR V1b, AVPR V3, antidiuretic hormone receptor 1B, arginine vasopressin receptor 3, pituitary vasopressin receptor 3, vasopressin V3 receptor, AVPR3, V1bR,)
• NCBI Gene ID: 553
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P47901
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

arginine vasopressin receptor 1B interacts with:

• G protein-coupled receptor kinase 5
  protein kinase C alpha

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.