UPB1, beta-ureidopropionase 1

UPB1, beta-ureidopropionase 1

• This gene encodes a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity. [provided by RefSeq, Jul 2008]

• Gene Synonyms (beta-ureidopropionase, beta-alanine synthase, n-carbamoyl-beta-alanine amidohydrolase, ureidopropionase, beta, BUP1,)
• NCBI Gene ID: 51733
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R1H3
  UNIPROT ID#>>Q9UBR1
  UNIPROT ID#>>B3KNC1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

beta-ureidopropionase 1 interacts with:

• acidic residue methyltransferase 1

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