ATP5MC1, ATP synthase membrane subunit c locus 1

ATP5MC1, ATP synthase membrane subunit c locus 1

• This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene is one of three genes that encode subunit c of the proton channel. Each of the three genes have distinct mitochondrial import sequences but encode the identical mature protein. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]

• Gene Synonyms (ATP synthase F(0) complex subunit C1, mitochondrial, ATP synthase lipid-binding protein, mitochondrial, ATP synthase proteolipid P1, ATP synthase proton-transporting mitochondrial F(0) complex subunit C1, ATP synthase subunit 9, ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9), ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9), ATP synthase, H+ transporting, mitochondrial Fo complex subunit C1 (subunit 9), ATPase protein 9, ATPase subunit 9, ATPase subunit C, mitochondrial ATP synthase, subunit 9, mitochondrial ATP synthase, subunit C, ATP5A, ATP5G, ATP5G1,)
• NCBI Gene ID: 516
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q6FIH7
  UNIPROT ID#>>P05496
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ATP synthase membrane subunit c locus 1 interacts with:

• beta-1,4-galactosyltransferase 3
  BMP/retinoic acid inducible neural specific 2
  butyrophilin subfamily 3 member A2
  C-terminal Src kinase
  fucosyltransferase 3 (Lewis blood group)
  leucine rich repeat and fibronectin type III domain containing 4
  OCIA domain containing 1
  protein O-mannose kinase
  TNF superfamily member 11
  tripartite motif containing 69
  ubiquilin 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.