MC3R, melanocortin 3 receptor

MC3R, melanocortin 3 receptor

• This gene encodes a G-protein-coupled receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone that is expressed in tissues other than the adrenal cortex and melanocytes. This gene maps to the same region as the locus for benign neonatal epilepsy. Mice deficient for this gene have increased fat mass despite decreased food intake, suggesting a role for this gene product in the regulation of energy homeostasis. Mutations in this gene are associated with a susceptibility to obesity in humans. [provided by RefSeq, Jul 2008]

• Gene Synonyms (BMIQ9, MC3, MC3-R, OB20, OQTL, melanocortin receptor 3, obesity quantitative trait locus,)
• NCBI Gene ID: 4159
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P41968
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

melanocortin 3 receptor interacts with:

• proopiomelanocortin

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.