KCNE1, potassium voltage-gated channel subfamily E regulatory subunit 1

KCNE1, potassium voltage-gated channel subfamily E regulatory subunit 1

• The product of this gene belongs to the potassium channel KCNE family. Potassium ion channels are essential to many cellular functions and show a high degree of diversity, varying in their electrophysiologic and pharmacologic properties. This gene encodes a transmembrane protein known to associate with the product of the KVLQT1 gene to form the delayed rectifier potassium channel. Mutation in this gene are associated with both Jervell and Lange-Nielsen and Romano-Ward forms of long-QT syndrome. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]

• Gene Synonyms (ISK, JLNS, JLNS2, LQT2/5, LQT5, MinK, potassium voltage-gated channel subfamily E member 1, IKs producing slow voltage-gated potassium channel subunit beta Mink, Long QT syndrome 5, cardiac delayed rectifier potassium channel protein, delayed rectifier potassium channel subunit IsK, minimal potassium channel, potassium channel, voltage gated subfamily E regulatory beta subunit 1, potassium voltage-gated channel, Isk-related family, member 1, potassium voltage-gated channel, Isk-related subfamily, member 1, voltage gated potassiun channel accessory subunit,)
• NCBI Gene ID: 3753
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q6FHJ6
  UNIPROT ID#>>A7LFK4
  UNIPROT ID#>>A7LFK2
  UNIPROT ID#>>P15382
  UNIPROT ID#>>C7S316
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

potassium voltage-gated channel subfamily E regulatory subunit 1 interacts with:

• potassium voltage-gated channel subfamily H member 2
  potassium voltage-gated channel subfamily Q member 1
  protein kinase C alpha
  tropomyosin 3
  ubiquitin associated and SH3 domain containing A

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.