KCTD1, potassium channel tetramerization domain containing 1

KCTD1, potassium channel tetramerization domain containing 1

• This gene encodes a protein containing a BTB (Broad-complex, tramtrack and bric a brac), also known as a POZ (POxvirus and zinc finger) protein-protein interaction domain. The encoded protein negatively regulates the AP-2 family of transcription factors and the Wnt signaling pathway. A mechanism for the modulation of Wnt signaling has been proposed in which the encoded protein enhances ubiquitination and degradation of the beta-catenin protein. Mutations in this gene have been identified in Scalp-ear-nipple (SEN) syndrome. [provided by RefSeq, May 2017]

• Gene Synonyms (BTB/POZ domain-containing protein KCTD1, C18orf5,)
• NCBI Gene ID: 284252
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q719H9
  UNIPROT ID#>>A0A024RC45
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

potassium channel tetramerization domain containing 1 interacts with:

• potassium channel tetramerization domain containing 1

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