ELF4, E74 like ETS transcription factor 4

ELF4, E74 like ETS transcription factor 4

• The protein encoded by this gene is a transcriptional activator that binds and activates the promoters of the CSF2, IL3, IL8, and PRF1 genes. The encoded protein is involved in natural killer cell development and function, innate immunity, and induction of cell cycle arrest in naive CD8+ cells. Two transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Jan 2010]

• Gene Synonyms (ELFR, MEF, ETS-related transcription factor Elf-4, E74-like factor 4 (ets domain transcription factor), myeloid Elf-1-like factor,)
• NCBI Gene ID: 2000
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q99607
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

E74 like ETS transcription factor 4 interacts with:

• F-box protein 4
  F-box protein 7
  H4 clustered histone 1
  lysine demethylase 5B
  MDM2 proto-oncogene
  nucleophosmin 1
  PML nuclear body scaffold
  SET nuclear proto-oncogene
  S-phase kinase associated protein 2
  ubiquitin B

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.