AIF1, allograft inflammatory factor 1

AIF1, allograft inflammatory factor 1

• This gene encodes a protein that binds actin and calcium. This gene is induced by cytokines and interferon and may promote macrophage activation and growth of vascular smooth muscle cells and T-lymphocytes. Polymorphisms in this gene may be associated with systemic sclerosis. Alternative splicing results in multiple transcript variants, but the full-length and coding nature of some of these variants is not certain. [provided by RefSeq, Jan 2016]

• Gene Synonyms (allograft inflammatory factor 1, interferon gamma responsive transcript, ionized calcium-binding adapter molecule 1, protein G1, AIF-1, IBA1, IRT-1, IRT1,)
• NCBI Gene ID: 199
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P55008
  UNIPROT ID#>>I3WTX1
  UNIPROT ID#>>Q4V347
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

allograft inflammatory factor 1 interacts with:

• heat shock transcription factor Y-linked 1
  lymphocyte cytosolic protein 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.