DMRT1, doublesex and mab-3 related transcription factor 1

DMRT1, doublesex and mab-3 related transcription factor 1

• This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous. [provided by RefSeq, Jul 2008]

• Gene Synonyms (doublesex- and mab-3-related transcription factor 1, DM domain expressed in testis 1, DM domain expressed in testis protein 1, CT154, DMT1,)
• NCBI Gene ID: 1761
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9Y5R6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

doublesex and mab-3 related transcription factor 1 interacts with:

• nanos C2HC-type zinc finger 3
  tripartite motif containing 29

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