DLX1, distal-less homeobox 1

DLX1, distal-less homeobox 1

• This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. The encoded protein is localized to the nucleus where it may function as a transcriptional regulator of signals from multiple TGF-{beta} superfamily members. The encoded protein may play a role in the control of craniofacial patterning and the differentiation and survival of inhibitory neurons in the forebrain. This gene is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 2. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

• Gene Synonyms (homeobox protein DLX-1, distal-less homeo box 1,)
• NCBI Gene ID: 1745
• Species: Homo sapiens (Human)
• UNIPROT ID#>>X5D2F9
  UNIPROT ID#>>P56177
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

distal-less homeobox 1 interacts with:

• forkhead box A1
  SMAD family member 4

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