DGKG, diacylglycerol kinase gamma

DGKG, diacylglycerol kinase gamma

• This gene encodes an enzyme that is a member of the type I subfamily of diacylglycerol kinases, which are involved in lipid metabolism. These enzymes generate phosphatidic acid by catalyzing the phosphorylation of diacylglycerol, a fundamental lipid second messenger that activates numerous proteins, including protein kinase C isoforms, Ras guanyl nucleotide-releasing proteins and some transient receptor potential channels. Diacylglycerol kinase gamma has been implicated in cell cycle regulation and in the negative regulation of macrophage differentiation in leukemia cells. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (diacylglycerol kinase gamma, DAG kinase gamma, diacylglycerol kinase, gamma 90kDa, diacylglyerol kinase gamma, diglyceride kinase gamma, DAGK3, DGK-GAMMA,)
• NCBI Gene ID: 1608
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P49619
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

diacylglycerol kinase gamma interacts with:

• succinate dehydrogenase complex flavoprotein subunit A

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