CRP, C-reactive protein

CRP, C-reactive protein

• The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. [provided by RefSeq, Sep 2009]

• Gene Synonyms (C-reactive protein, C-reactive protein, pentraxin-related, pentraxin 1, PTX1,)
• NCBI Gene ID: 1401
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P02741
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

C-reactive protein interacts with:

• 3'(2'), 5'-bisphosphate nucleotidase 2
  agrin
  beta-1,4-galactosyltransferase 3
  beta-1,4-galactosyltransferase 5
  beta-1,4-galactosyltransferase 7
  carbohydrate sulfotransferase 12
  carbohydrate sulfotransferase 3
  cell migration inducing hyaluronidase 2
  collagen type XVIII alpha 1 chain
  complement factor H
  contactin associated protein family member 3
  core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
  C-reactive protein
  ess-2 splicing factor homolog
  exostosin glycosyltransferase 1
  Fc fragment of IgG receptor Ia
  Fc fragment of IgG receptor IIa
  Fc fragment of IgG receptor IIb
  fibronectin 1
  GDP-mannose pyrophosphorylase A
  glutamate dehydrogenase 1
  glycoprotein VI platelet
  growth differentiation factor 11
  H1.1 linker histone, cluster member
  H2A clustered histone 16
  H2A clustered histone 20
  heparan sulfate 6-O-sulfotransferase 1
  laminin subunit alpha 1
  laminin subunit alpha 5
  laminin subunit beta 1
  laminin subunit beta 2
  laminin subunit gamma 3
  leptin
  mitogen-activated protein kinase 1
  mitogen-activated protein kinase 3
  mitogen-activated protein kinase 8 interacting protein 2
  N-deacetylase and N-sulfotransferase 2
  neurexophilin and PC-esterase domain family member 3
  peptide deformylase, mitochondrial
  protein tyrosine phosphatase receptor type S
  quiescin sulfhydryl oxidase 1
  ribosomal protein L13a
  ribosomal protein L23
  ribosomal protein L26 like 1
  serine protease 23
  small nuclear ribonucleoprotein U1 subunit 70
  spectrin beta, erythrocytic
  spermatid perinuclear RNA binding protein
  ST3 beta-galactoside alpha-2,3-sialyltransferase 4
  stanniocalcin 2
  TIMP metallopeptidase inhibitor 3
  ubiquitin protein ligase E3 component n-recognin 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.