CRMP1, collapsin response mediator protein 1

CRMP1, collapsin response mediator protein 1

• This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]

• Gene Synonyms (dihydropyrimidinase-related protein 1, dihydropyrimidinase-like 1, inactive dihydropyrimidinase, unc-33-like phosphoprotein 3, CRMP-1, DPYSL1, DRP-1, DRP1, ULIP-3,)
• NCBI Gene ID: 1400
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B3KT07
  UNIPROT ID#>>X5DNI1
  UNIPROT ID#>>Q96I11
  UNIPROT ID#>>B3KV96
  UNIPROT ID#>>Q14194
  UNIPROT ID#>>E9PD68
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

collapsin response mediator protein 1 interacts with:

• adaptor related protein complex 3 subunit mu 1
  ADP ribosylation factor GTPase activating protein 1
  ADP ribosylation factor like GTPase 15
  anterior gradient 2, protein disulphide isomerase family member
  armadillo repeat containing 1
  axin 1
  BTB domain containing 2
  C-C motif chemokine ligand 18
  CDK5 regulatory subunit associated protein 2
  CDK5 regulatory subunit associated protein 3
  cell division cycle associated 8
  chaperonin containing TCP1 subunit 7
  coiled-coil domain containing 106
  collapsin response mediator protein 1
  coronin 1B
  cullin 1
  DEAD-box helicase 18
  deoxyguanosine kinase
  dihydropyrimidinase like 2
  dihydropyrimidinase like 3
  DnaJ heat shock protein family (Hsp40) member B11
  DnaJ heat shock protein family (Hsp40) member B4
  dual specificity phosphatase 4
  dynein axonemal assembly factor 2
  epsin 1
  eukaryotic translation elongation factor 1 delta
  eukaryotic translation initiation factor 2 subunit beta
  exosome component 8
  far upstream element binding protein 1
  ferritin heavy chain 1
  FMR1 autosomal homolog 1
  glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
  golgin A2
  haloacid dehalogenase like hydrolase domain containing 2
  HCLS1 associated protein X-1
  heat shock protein family A (Hsp70) member 4
  heat shock protein family E (Hsp10) member 1
  hepatocyte growth factor-regulated tyrosine kinase substrate
  heterogeneous nuclear ribonucleoprotein H1
  heterogeneous nuclear ribonucleoprotein H3
  heterogeneous nuclear ribonucleoprotein U like 1
  high mobility group box 1
  huntingtin
  interleukin 33
  jumonji domain containing 6, arginine demethylase and lysine hydroxylase
  kelch like family member 20
  keratin 17
  leucine rich repeat containing 1
  leucine rich repeat kinase 2
  LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
  minichromosome maintenance complex component 3 associated protein
  mitochondrial ribosomal protein S12
  mitogen-activated protein kinase 8 interacting protein 2
  mitogen-activated protein kinase kinase kinase 20
  MOB family member 4, phocein
  N-acetyltransferase 9 (putative)
  NADH:ubiquinone oxidoreductase core subunit V2
  neurotrophic receptor tyrosine kinase 1
  nuclear FMR1 interacting protein 1
  nuclear VCP like
  OTU deubiquitinase 6B
  palmitoyl-protein thioesterase 1
  parvin alpha
  phospholipase A2 group IIA
  PITH domain containing 1
  platelet activating factor acetylhydrolase 1b catalytic subunit 3
  pleckstrin homology domain containing A4
  polyamine modulated factor 1
  profilin 1
  proteasome 26S subunit, non-ATPase 11
  protein phosphatase 1 regulatory subunit 8
  ral guanine nucleotide dissociation stimulator like 2
  receptor for activated C kinase 1
  regulator of G protein signaling 2
  replication protein A2
  reticulon 4
  Rho associated coiled-coil containing protein kinase 1
  ribosomal protein S6 kinase A5
  ribosomal RNA processing 7 homolog A
  SEC24 homolog C, COPII coat complex component
  selenophosphate synthetase 1
  serpin family B member 9
  small nuclear ribonucleoprotein polypeptide G
  spermidine/spermine N1-acetyltransferase 1
  spindle apparatus coiled-coil protein 1
  sprouty RTK signaling antagonist 2
  SRC proto-oncogene, non-receptor tyrosine kinase
  switching B cell complex subunit SWAP70
  thymidine kinase 1
  thyroid hormone receptor interactor 13
  trafficking from ER to golgi regulator
  TSC22 domain family member 1
  tubulin alpha 1a
  ubiquitin conjugating enzyme E2 A
  ubiquitin conjugating enzyme E2 B
  ubiquitin like modifier activating enzyme 5
  valosin containing protein
  vimentin
  YAE1 maturation factor of ABCE1
  zinc finger protein 24

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.