CEACAM5, CEA cell adhesion molecule 5

CEACAM5, CEA cell adhesion molecule 5

• This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]

• Gene Synonyms (carcinoembryonic antigen-related cell adhesion molecule 5, carcinoembryonic antigen related cell adhesion molecule 5, meconium antigen 100, CD66e, CEA,)
• NCBI Gene ID: 1048
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R0K5
  UNIPROT ID#>>Q53G30
  UNIPROT ID#>>P06731
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

CEA cell adhesion molecule 5 interacts with:

• CD209 molecule
  CEA cell adhesion molecule 6
  dispatched RND transporter family member 3
  estrogen receptor 2
  EWS RNA binding protein 1
  heterogeneous nuclear ribonucleoprotein M
  ubiquinol-cytochrome c reductase complex assembly factor 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.