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Tuesday, November 08, 2016
Betsy Herold, MD
Antibody dependent cell mediated cytotoxicity (ADCC) is an important immune effector mechanism against tumor and virus-infected cells. In recent years, ADCC has emerged as an important protective immune correlate in a number of vaccine studies for HIV and influenza. This webinar will highlight recent studies demonstrating the central role of FcR functions in vaccine-mediated protection against HSV-1 and HSV-2 infection, challenging the existing paradigm that high titer neutralizing antibodies are required.
Monday, October 31, 2016
Ms. Amy McGuckian
Forensic Biology Unit
Palm Beach County Sheriff’s Office
Dr. Anupama Gopalakrishnan
Screening for sperm in sexual assault samples is a laborious process with limited sensitivity compared to male DNA detection by amplification. Direct amplification of casework samples reduces the potential for DNA loss during purification, a special concern with low-template samples. In this webinar, Promega presents an overview of the Casework Direct Kit, and the Palm Beach County Sheriff’s Office describes how they plan to use the kit in their sexual assault evidence processing.
Tuesday, October 25, 2016
Michael M. Rosenblatt, PhD
Traditional protocols require digestion times of up to 18 hours, as well as reduction and alkylation prior to digestion. These denaturants often inhibit enzymes and modify proteins, and require removal prior to analysis. What if you could shorten digestion times to ~30 minutes, without denaturants or reductants or alkylating agents?
Tuesday, September 27, 2016
Richard Somberg, PhD
Therapeutic antibodies designed to block or activate immune checkpoint receptors are a powerful new approach to the treatment of cancer and other diseases. However, due to their biologic complexity the development of therapeutic antibodies requires unique functional and analytical tools. Here we present a suite of MOA-based functional bioassays for use in antibody screening, characterization, potency testing and stability studies.
Tuesday, August 23, 2016
Subhanjan Mondal, PhD
Cell Signaling is key to controlling cell health, and one key signaling node is GTPases. Technical options to analyze the biochemical activities of this incredibly important class of proteins are very limited. To support the needs of the research community, we will present various novel ways to analyze GTPase functions.