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Molecular Diagnostics (MDx)
Tuesday, June 12, 2018
Margaret L Gulley, MD
Circulating cell-free DNA can be used to monitor tumor burden and monitor disease progress. In part 3 of 3 ccfDNA webinars, Dr. Gulley discusses variables important to isolating high-quality ccfDNA from plasma samples including anticoagulant, plasma volume and storage length and conditions.
Tuesday, April 24, 2018
Douglas Horejsh, Ph.D.
The low concentration and highly fragmented nature of circulating cell-free DNA (ccfDNA), coupled with a low frequency of biomarkers of interest, present many challenges for ccfDNA purification and monitoring. In part 2 of 3 ccfDNA webinars, we will discuss techniques for maximizing results through proper sample handling, purification, quantitation, QC, and downstream processing of isolated cell-free DNA.
Tuesday, February 13, 2018
Research in circulating cell-free DNA (ccfDNA) has become a key area of interest in the study of normal and disease states. In this first of three ccfDNA webinars, we discuss the history and basics of ccfDNA – what is it, how do laboratories commonly extract ccfDNA, and what are typical applications for ccfDNA?
Wednesday, January 31, 2018
Alicia Cadenas and Rachel Oefelein
Forensic science laboratories are facing unprecedented change as more labs are analyzing and reporting DNA mixtures as a likelihood ratio (LR) using probabilistic genotyping software. This webinar covers the progress of probabilistic genotyping from training and implementation to casework results and courtroom experiences.
Tuesday, January 23, 2018
Matthew Robers, MS
Although a number of extracellular techniques exist to quantitatively measure kinase-ligand binding or inhibition, until now there was no means by which to quantitate target occupancy or drug affinity in live cells. In this webinar we report the use of an energy transfer technique (NanoBRET) in the first quantitative approach to profiling kinase occupancy of a test compound inside live cells.