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Home » Resources »

Promega Webinars

Welcome to the Promega Webinar Series, an ongoing communication designed to keep you informed. Learn about basic concepts, tips and techniques to help your research, or understand how products were designed and how to implement in your lab. Most presentations are given by Promega scientists and you will have an opportunity to interact with our Technical Service Scientist directly during live events via chat. The webinars are free though we do ask that you register for the events. Registration allows us to send you the URL for the webinar.

Biologics Forum: Tips and Tools for Successful Immunotherapy Bioassay Development

Drug Discovery

Tuesday, April 23, 2019

Zhijie Jey Cheng, PhD, Manuela Grassi, PhD and Richard Somberg, PhD

Mechanism of action (MOA)-based bioassays are a critical component of biologics drug development. However, establishing a functional bioassay that meets the regulatory guidelines for use in potency determination and lot release can be challenging. Join our panel of bioassay experts for a live discussion on bioassay design and selection, assay optimization, and bioassay qualification for potency lot release.

The Y-HRD Database: How It Works and How to Use It in Casework

Genetic Identity

Wednesday, May 08, 2019

Lutz Roewer, PhD

The Y-Chromosome Haplotype Reference Database (Y-HRD) includes Y-chromosome haplotype data from 135 national databases populated over the past 20 years. Y-based ancestry prediction and familial searching can provide important investigative leads. This webinar will discuss how to use the Y-HRD to facilitate statistical analyses for a range of casework applications and interpretation purposes (e.g., frequency estimation, kinship and mixture analysis and ancestry prediction).

Developing More Efficient Biologic Workflows with Automated Plasmid Preps and Protein/Antibody Purification


Tuesday, May 14, 2019

Dr. Nidhi Nath, Doug White and Chris D'Jamoos

Development and screening of biologics can be a time-consuming process due to the volume of samples processed for cloning, isolation of plasmids and purification of candidate antibodies. This webinar will discuss how our field-based automation team can help you develop walk-away automation solutions to speed up your purification workflow.

Studying Endogeneous Protein Dynamics with CRISPR-Mediated Tagging: Understanding Your Options

Cell-Based Assays

Tuesday, June 04, 2019

Christopher Eggers, PhD

An exciting application of CRISPR/Cas9-mediated gene editing is the ability to tag and measure endogenously expressed proteins while maintaining native expression levels and regulation. In this webinar, we will discuss available options for simple and efficient knock-in of a bioluminescent peptide tag to enable sensitive, homogeneous assays for measuring protein dynamics.

Did you miss one of our webinars? Simply select the appropriate link below and view the recorded webinar. It will not be interactive, but you will see the chat questions the original attendees asked. For additional information on the products discussed in the webinar, explore our links to videos and other resources.

If there is an area you would like to see covered, you can request a topic of your choice.

If you are experiencing issues opening the webinar recordings, please be sure that you have the latest Adobe Flash Player installed.

Targeting Proteins for Degradation: Characterizing PROTAC Kinetics and Mode of Action Using Live-Cell Assays

Cell-Based Assays

Tuesday, November 13, 2018

Kristin M. Riching

Despite the promising potential of PROTAC compounds in new drug discovery strategies, interrogating the multiple steps required to achieve effective PROTAC-mediated target protein degradation remains a challenge. This webinar will describe a platform of live-cell assays that can be used to measure real-time degradation kinetics and key cellular protein interactions mediating the degradation process. Join us to learn how these tools can be used to improve functional and cellular characterization of your PROTAC compounds.

Application of BRET Technology to Quantitatively Determine Kinase Inhibitor Potency in Live Cells

Drug Discovery

Tuesday, November 06, 2018

Matthew Robers and Kelvin Lam

Methods for measuring kinase inhibitor potency in live cells are limited. In this webinar, we describe how the NanoBRET™ Target Engagement technique is overcoming technical limitations of existing methods by broadly enabling quantitative determination of kinase inhibitor occupancy in live cells. We also discuss a collaboration between Promega and Reaction Biology Corporation that has enabled conversion of these assays into a service compatible with high-throughput cell-based profiling.

A Multimodal Assay for Quantitating and Interpreting Changes in Autophagic Flux

Cell-Based Assays

Tuesday, October 23, 2018

Dan Lazar, PhD and Gary Allenby, PhD

Monitoring autophagy using imaging or western blotting methods can be cumbersome, low-throughput and subjective. Learn about a new LC3 reporter assay with three modalities (plate-reader based, imaging and blotting) to help scale up your autophagy analysis with confidence.

Bottoms Up: Improving Proteomic Sample Preparation with Recombinant Asp-N and Multi-Enzyme Workflows


Tuesday, October 16, 2018

Chris Hosfield, PhD

While trypsin is the workhorse for bottom-up proteomics, it is not a magic bullet since tryptic digestion often leaves gaps in protein sequences. In this webinar Dr. Hosfield will describe the advantages of using a new recombinant Asp-N protease to fill in the gaps. He will also demonstrate how combining digests from multiple proteases can yield comprehensive sequence coverage of proteins from a single LC-MS/MS run.

Ask the Experts: Ensuring a Successful PCR Every Time


Tuesday, September 11, 2018

Natascha Buter, MS and Joliene Lindholm, PhD

Do you have questions about PCR? Our Technical Support Scientists Natascha Buter and Joliene Lindholm will be answering all your questions about nucleic acid amplification. Learn more about endpoint PCR and how to make sure you have a successful run every time.

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