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Validation Guide for the DNA IQ™ Reference Sample Kit for Maxwell® 16

Abstract

This guide suggests experiments to be performed with the DNA IQ™ Reference Sample Kit for Maxwell® 16 for internal validation. A suggestion on the minimal number of samples that need to be processed is provided at the end. These studies are intended to show that the automated system yields DNA templates with subsequent STR genotypes that are concordant with current manual extraction procedures used in the laboratory and have no detectable levels of cross-contamination. In addition, when using the DNA IQ™ System, this validation study will demonstrate the consistency of yields obtained within the various reference or database sample types routinely extracted in the laboratory and provide the mean expected yields from these types of samples.