Our website does not fully support your browser.

We've detected that you are using an older version of Internet Explorer. Your commerce experience may be limited. Please update your browser to Internet Explorer 11 or above.

We believe this site might serve you best:

United States

United States

Language: English

Promega's Cookie Policy

Our website uses functional cookies that do not collect any personal information or track your browsing activity. When you select your country, you agree that we can place these functional cookies on your device.

SignaTECT® DNA-Dependent Protein Kinase Assay System Technical Bulletin

Instructions for Use of Product(s)
V7870

Literature # TB250

The SignaTECT® DNA-Dependent Protein Kinase Assay System provides an improved method to quantitate DNA-dependent protein kinase (DNA-PK) activity in both purified enzyme preparations and cell nuclear extracts. The SignaTECT® System uses the unique SAM2® Biotin Capture Membrane, produced by a proprietary process that results in a high density of streptavidin on the membrane matrix.
The SignaTECT® DNA-PK Assay System overcomes the problem of nonspecific substrate binding by using a biotinylated DNA-PK p53-derived peptide substrate in conjunction with the SAM2® Biotin Capture Membrane. The high binding capacity of the SAM2® Biotin Capture Membrane for the DNA-PK biotinylated peptide substrate and low backgrounds observed with this system maximize the signal-to-noise ratio.

Printed in USA. Revised 1/13.