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AAI 2020 Virtual Booth

April 30 - June 21, 2020

Welcome to our virtual booth for the American Association of Immunologists annual meeting IMMUNOLOGY2020™. Here you can keep up with the latest information on our assays for immunology research. Explore all the highlights that you would have seen from the real Promega booth!

New Product: Lumit™ Immunoassays

Replace conventional immunoassays, such as Western blots and ELISAs, with new Lumit™ Immunoassays. These no-wash assays offer direct luminescence measurement in cell culture, broad dynamic range, and can be completed in as little as 30 minutes.

Lumit™ Immunoassays are available for a range of applications, including protein phosphorylation and pathway analysis, FcRn binding, cytokine detection, metabolism research and more. You can also build your own Lumit™ Immunoassays with our labeling and detection kits.

Learn More

Lumit immunoassay principle

General principle of a Lumit™ Immunoassay. Antibodies are chemically labeled with the small and large subunits of NanoLuc® Luciferase, known as SmBiT and LgBiT, respectively. In the presence of an analyte, the two antibodies come into close proximity, allowing SmBiT and LgBiT to form an active enzyme and generate a bright luminescence signal.


Lumit™ Immunoassay Poster

Chris Heid

Lumit™ Immunoassays: Bioluminescent, Sensitive, and Homogeneous Analyte Detection Using Labeled Antibodies

Presented by Chris Heid, Sr. Global Commercialization Marketing Manager

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Lumit™ Immunoassay Webinar: An Easier, Faster Method for Analyte Detection

Detecting analytes is often performed using heterogeneous methods such as Western blotting and ELISAs. Western blotting requires separation and transfer steps while ELISAs involve lots of procedural steps, and both methods often require overnight incubations. Join us to learn about the Lumit™ Immunoassay technology and how it can simplify your workflow and yield results faster! This webinar will also include a live Q&A session to address any questions you might have about the assay technology.

Date: Wednesday, May 13, 2020

Time: 10:00 am CDT (11:00 am EDT)

Register Now

Immunometabolism

Cells of the tumor microenvironment must compete for fuels and respond to changing, dysregulated conditions to remain viable and functional. Identifying the metabolic requirements and vulnerabilities of tumor and immune cells in this environment can lead to more effective cancer treatments.

We provide a series of bioluminescent metabolite detection assays for monitoring key cell metabolic pathways such as:

The assays share a common NAD(P)H bioluminescent detection technology and were developed to have high sensitivity, an important feature when samples are limiting and contain only a few cells or small volumes.

Immunometabolism Poster

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Sensitive Bioluminescent Assays for Monitoring Changes in Tumor and Immune Cell Metabolism

Presented by Donna Leippe, Sr. Research Scientist

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Immunotherapy Bioassays

We provide reporter bioassays to characterize and develop novel monoclonal antibody and cell-based therapeutics. These assays are useful for interrogating a range of biological functions, including Fc effector activity, immune checkpoint modulation, T cell activation and cytokine and growth factor signaling.

Bioassay Poster Presentations

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Novel Bioluminescent Bioassays for the Discovery and Development of Molecular and Cellular T-Cell Redirecting Cancer Therapy

Presented by Jey Cheng, Sr. Research Scientist

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Richard Moravec

Reproducible, MoA-reflecting Reporter-Based Bioassays to Enable Drug Development of Biosimilars and Biobetters

Presented by Richard Moravec, Sr. Research Scientist

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Developing a Bioluminescent PBMC ADCC Assay for the Discovery and Characterization of Therapeutic Antibodies

Presented by Jey Cheng, Sr. Research Scientist

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Quantitative Cell-Based Bioassays to Advance Immunotherapy Programs Targeting Immune Checkpoint Receptors

Presented by Jamison Grailer, Sr. Research Scientist

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Interested in more information about functional bioassays?

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