Drug Discovery Chemistry 2022
April 18, 2022 - April 21, 2023
Hilton Bayfront
San Diego CA
Drug Discovery Chemistry is an event focused on the discovery and optimization challenges of small molecule drug candidates. Check out the products and technologies we are featuring at DDC 2022.
Featured Products & Technologies
Targeted Protein Degradation
Explore 150+ CRISPR-edited cell lines for studying protein degradation targets, and services for custom cell-line development and protein degradation profiling.
Study protein degradation in real time using CRISPR knock-in cell lines. Read the White Paper.
RAS Signaling Pathways
RAS is the most frequently mutated oncogene in human cancers, and KRAS is the most frequently mutated subtype of the RAS family. Discover assays and technologies to probe RAS and KRAS biology, including target engagement, protein:protein interactions, protein levels and activation of ERK.
Kinase Biology
Bioluminescent assays can help determine the ability of compounds to bind or inhibit kinases in biochemical and cellular formats, and are amenable to high-throughput or selectivity profiling. NanoBRET™ Target Engagement Assays enable you to quantify live-cell target engagement to quantitate compound affinity and residence time, and calculate cellular compound permeability.
Protein:Protein Interactions
The extreme brightness and small size of NanoLuc® luciferase make it possible to label proteins with less risk of interfering with natural function, detecting protein interactions in live cells under native conditions.
Fast, No-Wash Lumit™ Immunoassays
Quantify proteins or small molecules without tedious wash steps! Our homogeneous Lumit™ Immunoassays are sensitive, have broad dynamic range and can be completed in 70 minutes or less.
Assay Development Services
Our Tailored R&D Solutions team provides custom services to help accelerate your small molecule drug discovery and development. These comprehensive services are built around award-winning bioluminescent technology for sensitive, high-throughput and biologically relevant results.
Posters & Presentations
All scientific posters will be available for download following the presentation of the final poster on April 21.
Featured Presentation
BRET Probes for Profiling Reversible Engagement of RAS in Live Cells
Presented by: Joel Walker
Thursday, April 21 | 12:40 pm
Scientific Posters
NanoBRET as a Live Cell Method to Assess PROTAC Affinity & Intracellular Availability for E3 Ligases
Presented by: Kara Machleidt
View PDF Presentation
Broad Spectrum Cellular Kinase Selectivity Profiling in Live Cells with NanoBRET™ Technology
Presented by: Kara Machleidt
View PDF Presentation
Reversible Switch-II Pocket Engagement Across KRAS Hotspot Mutants in Cells
Presented by: Joel Walker
View PDF Presentation
Lumit™ Protein Interaction Immunoassays Using Protein Tags and Biotinylated Small Molecules
Presented by: Steven Edenson
View PDF Presentation
Unlocking Targeted Protein Degradation
Presented by: Steven Edenson
View PDF Presentation