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AACR 2020 Resources

June 22 - September 24, 2020

Virtual

New products, instruments, posters, online presentation and resources for cancer research.

Promega is committed to supporting SARS-CoV-2 research and vaccine development. Learn More

Looking to Connect?

We would love to speak with you, one on one, about your research interests. Please fill out the information request form and a Promega representative will be in touch.

 

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Poster Presentations

dan-lazar-125x125Real-Time Monitoring of PROTAC and Molecular Glue Targeted Degradation in Living Cells
Presented by Kristin Riching

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samantha lewisA Performance Characterization of Microsatellite Instability and Mismatch Repair Testing Methods in Endometrial Samples
Presented by Samantha Lewis

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julia gildenNovel Bioluminescent Bioassays for the Discovery and Development of Molecular and Cellular T-Cell Redirecting Cancer Therapy
Presented by Julia Gilden

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jamison grailerQuantitative Cell-Based Bioassays to Advance Immunotherapy Programs Targeting Immune Checkpoint Receptors
Presented by Jamison Grailer

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dan lazarRapid and Sensitive Determination of Cytokine Release from Cells without the Need for Sample Transfer
Presented by Dan Lazar

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jey chengA Homogenous PBMC ADCC Bioassay Enables Bridging Studies with ADCC Reporter Bioassays in Immunotherapy Monoclonal Antibody Development
Presented by Jey Cheng

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Chris HeidTargeted Degradation of Endogenously Tagged Proteins for Phenotypic Studies using HaloPROTAC3 and HaloTag® Technologies
Presented by Chris Heid

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steve edensonReproducible, MoA-Reflecting Reporter-Based Bioassays to Enable Drug Development of Biosimilars and Biobetters
Presented by Steve Edenson

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Drew NilesA Real-Time Extracellular ATP Assay to Identify Modulators of the Innate Immune Response
Presented by Drew Niles

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jim vastaLive Cell CDK Inhibitor Profiling Confirms Selectivity for Key Drugs and Reveals Opportunities for Inhibitor Repurposing
Presented by Jim Vasta

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matt robersNanoBRET™ in Live Cells as a Method to Assess E3 Ligase and Target Protein Occupancy for PROTACs
Presented by Matt Robers

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jonathan mitchellCell-Based Reporter Bioassays for Development of Fc-Functional and Fc-Silent SIRPa/CD47 Checkpoint Inhibitors
Presented by Jonathan Mitchell

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Product Information and Resources

Learn more about how Promega is helping advance cancer research, from the laboratory to the clinic, with innovative products and technology platforms.


Clinical Research

With many urgent challenges and uncertain outcomes, molecular oncology research requires comprehensive support and resources. We believe in science-driven solutions and personalized service for scientists working with any type of cancer research. Explore our collection of molecular oncology resources, or chat with a scientist to work through your specific needs.

What is Microsatellite Instability (MSI)?


Biologics

We provide a broad portfolio of functional bioassays and monoclonal antibody characterization tools to accelerate your biologics drug discovery and development. Our custom assay development team can partner with drug developers in the early stages of biologic development to ensure that our bioassays meet your needs.

Biologics for Drug Discovery

Cell Viability, Toxicity, & Metabolism

We offer many products to assist your cell biology studies. Our products include assays to monitor cell health and apoptosis, oxidative stress, inflammation and changes in energy metabolism. All our kits are scalable for high-throughput screening and drug discovery applications, and many of our assays have been validated for use in 3D culture.

Cell Viability and Cytotoxicity

Protein Dynamics & Cell Signaling

Promega’s unique portfolio of products to study real-time protein dynamics are based on innovative bioluminescent technology. These methods are useful for detecting and studying proteins at endogenous expression levels.

New Products

Lumit™ Immunoassays

Replace conventional immunoassays, such as Western blots and ELISAs, with new Lumit™ Immunoassays. These assays offer direct luminescence measurement in cell culture, broad dynamic range, and can be completed in as little as 30 minutes.

Lumit™ Immunoassays are available for a range of applications, including protein phosphorylation and pathway analysis, FcRn binding, cytokine detection, metabolite research, and more. You can also build your own Lumit™ immunoassays with our labeling and detection kits.

Our Lumit™ Immunoassay webinar introduces the technology and provides examples of applications for cytokine detection, signaling pathway analysis and FcRn binding.

Learn More

View Webinar On Demand

Lumit immunoassay principle

General principle of a Lumit™ Immunoassay. Antibodies are chemically labeled with the small and large subunits of NanoLuc® Luciferase, known as SmBiT and LgBiT, respectively. In the presence of an analyte, the two antibodies come into close proximity, allowing SmBiT and LgBiT to form an active enzyme and generate a bright luminescence signal.

Technology Platforms to Support Cancer Research

Spectrum Compact CE Instrument for Sanger Sequencing

Spectrum Compact CE System
One compact capillary electrophoresis system optimized for fragment analysis

GloMax Discover System Multimode Plate Reader

GloMax® Discover Microplate Reader
State-of-the-art luminescence, fluorescence, UV-visible absorbance, BRET and FRET detection

RSC48_front2

Maxwell® RSC 48 Instrument
High-quality nucleic acid purification with minimal steps and less hands-on time