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Primary Screening

Biochemical and cell-based assays, including live-cell assays, for target and cell health assessment. Targets are wide-ranging, such as kinase activity and inhibition, GPCR/GTPases, drug target & protein interactions, metabolite detection, oxidative stress, methyltransferase activity and histone deacetylases. All tools are suitable for high-throughput screening in identifying target inhibitory compounds.

31 Products


Target Class


Technique


Sample Type


Detection Method

Shop all Primary Screening

HaloTag® Technology for Protein Analysis

Custom HaloTag® Vectors, functional ligands and live-cell protein interaction assays.

Luciferase Pathway Reporters

Prebuilt luciferase vectors and cell lines for studying signaling pathways.

NanoBRET™ Target Engagement BET BRD Assays

Directly measure BET bromodomain-test compound affinity and residence time in live cells.

N2131, N2180, N2130, N2140

Glucose Uptake-Glo™ Assay

Non-radioactive assay for measuring glucose uptake.

J1341, J1342, J1343

MTase-Glo™ Methyltransferase Assay

Measure methyltransferase activity using a universal bioluminescent assay.

V7601, V7602

MethylEdge® Bisulfite Conversion System

Rapid bisulfite conversion with minimal DNA fragmentation.

N1301

ONE-Glo™ EX Luciferase Assay System

Improved ONE-Glo™ Assay. Higher sensitivity, long-lived luminescence, more storage options.

E8110, E8120, E8130, E8150

RealTime-Glo™ MT Cell Viability Assay

A bioluminescent method to kinetically monitor viability in cell culture up to 72 hours.

G9711, G9712, G9713

Coincidence Reporter Vectors

Four vectors with and without promoters that express both firefly and NanoLuc® luciferases from the same transcript for identifying false hits during screening.

N1461, N1471, N1481, N1491

HDAC-Glo™ Class IIa and HDAC-Glo™ 2 Assays

Detects HDAC Class IIa and Class I enzyme 2 activity.

G9560, G9590

ViaFect™ Transfection Reagent

High-efficiency, low-toxicity transfection of many cell types, including iPS cells.

E4981, E4982

NanoBRET™ Target Engagement Assay Components

For use with NanoBRET™ TE BET BRD and HDAC Assays.

N2150, N2120, N2161, N2160, N2191, E4881

Nano-Glo® Luciferase Assay System

Add-mix-measure assay for NanoLuc® Luciferase with >2 hour half-life in most applications.

N1110, N1120, N1130, N1150

FuGENE® 6 Transfection Reagent

Proven, dependable performance. Best for everyday use with common cell lines.

E2691, E2692, E2693

HDAC-Glo™ I/II Assays and Screening System

Detects HDAC class I and II enzyme activity.

G6420, G6421, G6422, G6430, G6431

Showing 31 of 31 Products

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