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Promega Corporation

IdeS Protease and IdeZ Protease

IdeS Protease
IdeS Protease is an immunoglobulin-degrading enzyme from Streptococcus pyogenes (IdeS). It is an engineered recombinant protease overexpressed in E. coli that cleaves Immunoglobulin G (IgG) with high specificity at a single site below the hinge region, yielding F(ab’)2 and Fc fragments. The protocol for a standard reaction is to add the IdeS Protease to the IgG sample, add 1 unit of IdeS Protease per 1µg of IgG to be digested and incubate the sample at 37°C for 30–60 minutes in a neutral pH buffer.

IdeZ Protease
IdeZ Protease is an immunoglobulin-degrading enzyme from Streptococcus ...

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  • *Prices valid for US customers only
Product Size Conc. Catalog # *List Price QTY Add to Cart

IdeS Protease

5,000 units
- V7511 $ 892.00 Add to cart

IdeS Protease

25,000 units
(5 × 5,000 units)
- V7515 $ 3,894.00 Add to cart

IdeS Protease, Frozen

2,000 units
50u/μl V7512 $ 464.00 Add to cart

IdeZ Protease

5,000 units
- V8341 $ 875.00 Add to cart

IdeZ Protease

25,000 units
(5 × 5,000 units)
- V8345 $ 3,818.00 Add to cart

IdeZ Protease, Frozen

2,000 units
50u/μl V8342 $ 473.00 Add to cart


Storage Conditions

Store IdeS Protease at –30°C to –10°C. Store IdeZ Protease at –30°C to –10°C.

For product intended use please see Patents & Disclaimers tab.

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