PowerPlex® Fusion 6C System

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6-Color Co-Amplification and Detection of 27 Loci

  • Amplify all loci in the expanded CODIS core loci (including 23 autosomal STRs, 3 Y-STRs and Amelogenin)
  • Direct-amplification protocols and rapid cycling capabilities reduce processing time for all samples
  • High inhibitor tolerance and sensitivity for casework

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Catalog number selected: DC2705

$ 1,498.00
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PowerPlex® Fusion 6C System
50 (or 100 direct-amp) reactions
$ 1,498.00
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Highest Inter-Database Compatibility and Discrimination

The PowerPlex® Fusion 6C System provides all of the materials needed for co-amplification and fluorescent detection of 27 loci, including the CODIS core loci and European Standard Set (ESS) loci, and Amelogenin and DYS391 for gender determination. The Penta D, Penta E, TPOX, D22S1045 and SE33 loci are also included. Finally, two rapidly mutating Y-STR loci, DYS570 and DYS576, are included in the multiplex. This comprehensive set supports compatibility with present databases across multiple regions and encompasses an expanded set of loci to address future growth. The PowerPlex® Fusion 6C System delivers more information and high success rates from demanding forensic, paternity and relationship-testing cases.

ForensicGrade

Promega forensic products are manufactured in alignment with the ISO 18385 standard. This standard ensures minimal risk of human DNA contamination for products used to collect, store and analyze biological materials for forensic purposes. Learn more.

High Discriminatory Power

The Probability of Identity value achieved with the PowerPlex® Fusion loci set is exceptional. By combining US CODIS and ESS loci, the system offers significant gains in discriminatory power and helps ensure fewer adventitious matches are obtained.

A probability of identity value (PI) is defined as the probability that two individuals selected at random will have an identical genotype at the tested locus.

STR Kit Number of Loci PI* (N = 1036)
GlobalFiler™ STR Kit 23 1.63 × 10–27
Investigator® 24plex Kit 23 1.63 × 10–27
PowerPlex® Fusion System 24 1.38 × 10–28
PowerPlex® Fusion 6C System 27 9.09× 10–31

*Note: PI values do not include Amelogenin or Y-STRs.

Reference: Steffen, C.R. et al. (2017) FSI Genetics Corrigendum to ‘U.S. Population Data for 29 Autosomal STR Loci’. doi: https://doi.org/10.1016/j.fsigen.2017.08.011

Superior Sensitivity

The PowerPlex® Fusion 6C System reliability produces complete STR profiles from as little as 125pg of human DNA and usable, partial profiles from DNA amounts lower than 125pg.

12561MB-W-a

PowerPlex® Fusion 6C System

12561MB-W-b

GlobalFiler® PCR Amplification Kit

Enhanced Inhibitor Tolerance

The PowerPlex® Fusion 6C System can successfully meet the challenges of inhibitor-laden samples, increasing your success rate and minimizing the need to re-amplify samples.

12560MB-W

Direct-Amplification Compatibility for Most Sample Types

The PowerPlex® Fusion 6C System enables direct amplification with 12.5μl reactions from numerous sample types, including FTA® card punches, pretreated nonFTA cards (data not shown) and commonly used swabs. Laboratories can streamline their workflow while stretching their budget.

12562MA-W

Direct amplification of two 1.2mm punches from a buccal sample on an FTA® card using the recommended protocol for 12.5μl reactions.

FTA® Card Punches

12563MA-W

A buccal swab was pretreated with SwabSolution™ Reagent as recommended in the SwabSolution™ Kit Technical Manual. Following incubation, 2μl of extract was added to the PCR amplification mix using the recommended protocol for 12.5μl reactions.

Swab

Rapid Processing Solutions for PowerPlex® Systems

The 5X AmpSolution™ Reagent, SwabSolution™ Kit and PunchSolution™ Kit allow fast and simple processing of swabs and punches for analysis with various PowerPlex® Systems, including the PowerPlex® 21, 18D, 16HS, ESX, ESI, CS7 and Y23 Systems. These products are intended for preparation of single-source reference, database and paternity samples where sample purification is unnecessary.

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Specifications

You are viewing: DC2705 Change Configuration

What's in the box?

Item Part # Size Concentration Available Separately

2800M Control DNA

DD710A 1 × 25μl 10ng/μl View Product

PowerPlex® Fusion 6C Allelic Ladder Mix

DG417B 1 × 25μl

WEN Internal Lane Standard 500

DG500A 1 × 200μl View Product

PowerPlex® Fusion 6C 5X Primer Pair Mix

DK419B 1 × 250μl

PowerPlex® Fusion 6C 5X Master Mix

DP114A 1 × 250μl

Water, Amplification Grade

DW099A 1 × 1,250μl View Product

Certificate of Analysis

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Use Restrictions

Not For Medical Diagnostic Use.

Storage Conditions

EE

Patents and Disclaimers

U.S. Pat. No. 9,139,868, European Pat. No. 2972229, Japanese Pat. No. 6367307 and other patents pending.

TMR-6C, CXR-6C, TOM-6C and WEN-6C dyes are proprietary.

Specifications

You are viewing: DC2720 Change Configuration

What's in the box?

Item Part # Size Concentration Available Separately

2800M Control DNA

DD710A 1 × 25μl 10ng/μl View Product

PowerPlex® Fusion 6C Allelic Ladder Mix

DG417B 4 × 25μl

WEN Internal Lane Standard 500

DG500A 2 × 200μl View Product

PowerPlex® Fusion 6C 5X Primer Pair Mix

DK419B 4 × 250μl

PowerPlex® Fusion 6C 5X Master Mix

DP114A 4 × 250μl

Water, Amplification Grade

DW099A 5 × 1,250μl View Product

Certificate of Analysis

Search by lot number

Use Restrictions

Not For Medical Diagnostic Use.

Storage Conditions

EE

Patents and Disclaimers

U.S. Pat. No. 9,139,868, European Pat. No. 2972229, Japanese Pat. No. 6367307 and other patents pending.

TMR-6C, CXR-6C, TOM-6C and WEN-6C dyes are proprietary.

Specifications

You are viewing: DC2780 Change Configuration

What's in the box?

Item Part # Size Concentration Available Separately

2800M Control DNA

DD710A 1 × 25μl 10ng/μl View Product

PowerPlex® Fusion 6C Allelic Ladder Mix

DG417C 4 × 100μl

WEN Internal Lane Standard 500

DG500A 5 × 200μl View Product

PowerPlex® Fusion 6C 5X Primer Pair Mix

DK419C 4 × 1,000μl

PowerPlex® Fusion 6C 5X Master Mix

DP114B 4 × 1,000μl

Water, Amplification Grade

DW099A 10 × 1,250μl View Product

Certificate of Analysis

Search by lot number

Use Restrictions

Not For Medical Diagnostic Use.

Storage Conditions

EE

Patents and Disclaimers

U.S. Pat. No. 9,139,868, European Pat. No. 2972229, Japanese Pat. No. 6367307 and other patents pending.

TMR-6C, CXR-6C, TOM-6C and WEN-6C dyes are proprietary.

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