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PowerPlex® Fusion 6C System

6-Color Co-Amplification and Detection of 27 Loci

  • Amplify all loci in the expanded CODIS core loci (including 23 autosomal STRs, 3 Y-STRs and Amelogenin)
  • Direct-amplification protocols and rapid cycling capabilities reduce processing time for all samples
  • High Inhibitor tolerance and sensitivity for casework

Size

Catalog number selected: DC2705

$ 1,300.00 Your price: Log In

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PowerPlex® Fusion 6C System
50 (or 100 direct-amp) reactions
$ 1,300.00
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32464067_WB-GI-FusionHero

Highest Inter-Database Compatibility and Discrimination

The PowerPlex® Fusion 6C System provides all of the materials needed for co-amplification and fluorescent detection of 24 loci, including the CODIS core loci and European Standard Set (ESS) loci, and Amelogenin and DYS391 for gender determination. The Penta D, Penta E, TPOX, D22S1045 and SE33 loci are also included these loci. Finally, two rapidly mutating Y-STR loci, DYS570 and DYS576, are included in the multiplex. This comprehensive set supports compatibility with present databases across multiple regions and encompasses an expanded set of loci to address future growth. The PowerPlex® Fusion 6C System delivers more information and high success rates from demanding forensic, paternity and relationship-testing cases.

ForensicGrade

Promega forensic products are manufactured in alignment with the ISO 18385 standard.This standard ensures minimal risk of human DNA contamination for products used to collect, store and analyze biological materials for forensic purposes. Learn more.

High Discriminatory Power

The Probability of Identity value achieved with the PowerPlex® Fusion loci set is exceptional. By combining US CODIS and ESS loci, the system offers significant gains in discriminatory power and helps ensure fewer adventitious matches are obtained.

A probability of identity value (PI) is defined as the probability that two individuals selected at random will have an identical genotype at the tested locus.

STR KitNumber of LociPI (N = 1036)
CODIS 13
13
5.02 × 10-16
ESS 12
12
3.04 × 10-16
CODIS 20
20
9.35 × 10-24
GlobalFiler™ STR Kit
23
7.73 × 10-28
Investigator® 24plex Kit
23
7.73 × 10-28
PowerPlex® Fusion System
24
6.58 × 10–29
PowerPlex® Fusion 6C System
27
2.30 × 10-32

Note: PI values do not include Amelogenin.

Reference:
Butler, J.M., Hill, C.R. and Coble, M.D. Variability of new STR loci and kits in US population groups. Profiles in DNA https://www.promega.com/resources/profiles-in-dna/2012/variability-of-new-str-loci-and-kits-in-us-population-groups/ Published 2012. Accessed April, 2012.

Superior Sensitivity

The PowerPlex® Fusion 6C System reliability produces complete STR profiles from as little as 125pg of human DNA and usable, partial profiles from DNA amounts lower than 125pg.

PowerPlex® Fusion 6C System

12561MB-W-a

GlobalFiler® PCR Amplification Kit

12561MB-W-b

Enhanced Inhibitor Tolerance

The PowerPlex® Fusion 6C System can successfully meet the challenges of inhibitor-laden samples, increasing your success rate and minimizing the need to re-amplify samples.

12560MB-W

Human genomic DNA (500pg) was amplified with each listed kit in the presence of common PCR inhibitors.

Direct-Amplification Compatibility for Most Sample Types

The PowerPlex® Fusion 6C System enables direct amplification with 12.5μl reactions from numerous sample types, including FTA® card punches, pretreated nonFTA cards (data not shown) and commonly used swabs. Laboratories can streamline their workflow while stretching their budget.

FTA® Card Punches

12562MA-W

Direct amplification of two 1.2mm punches from a buccal sample on an FTA® card using the recommended protocol for 12.5μl reactions.

Swab

12563MA-W

A buccal swab was pretreated with SwabSolution™ Reagent as recommended in the SwabSolution™ Kit Technical Manual. Following incubation, 2μl of extract was added to the PCR amplification mix using the recommended protocol for 12.5μl reactions.

Rapid Processing Solutions for PowerPlex®

The 5X AmpSolution™ Reagent, SwabSolution™ Kit and PunchSolution™ Kit allow fast and simple processing of swabs and punches for analysis with various PowerPlex® Systems, including the PowerPlex® 21, 18D, 16HS, ESX, ESI, CS7 and Y23 Systems. These products are intended for preparation of single-source reference, database and paternity samples where sample purification is unnecessary.

Which Product is Right for Me?

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ID_Automation

Want to Automate?

Want to spend more time on STR data analysis? Let the STR Normalization Manager Software set up your PCR amplifications using the Biomek® 4000 (Beckman Coulter), Freedom EVO (Tecan) or MicroLab STAR (Hamilton) liquid handlers. The software uses quantitation data from the PowerQuant® or Plexor® HY Systems to accurately dilute and set up STR amplification of extracted DNA. The software can also set up direct amplification from swabs and card punches.

Automate Your STR Setup

Contact your local representative to receive a quote for the required quantities and to purchase and schedule the required installation and training services.

Learn more
Consumables
Product Size Cat. #
1.1ml, Square-Well V-bottom Deep Well Plate
25/pack
2.2ml, Square-Well Deep Well Plate
50/pack
Water, Amplification Grade
6,250ml
Hardware
Product Cat. #
Four-Position Tube Holder
Heat Block Adapter
Plate Clamp 96
Plate Stand
Software
Product Cat. #
STR Normalization Manager Software

Specifications

You are viewing: DC2705 Change Configuration

What's in the box?

Item Part # SizeConcentrationAvailable Separately

2800M Control DNA

DD710A 1 × 25μl10ng/μl View Product

PowerPlex® Fusion 6C Allelic Ladder Mix

DG417B 1 × 25μl

WEN Internal Lane Standard 500

DG500A 1 × 200μl View Product

PowerPlex® Fusion 6C 5X Primer Pair Mix

DK419B 1 × 250μl

PowerPlex® Fusion 6C 5X Master Mix

DP114A 1 × 250μl

Water, Amplification Grade

DW099A 1 × 1,250μl View Product

SDS

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Certificate of Analysis

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Use Restrictions

Not For Medical Diagnostic Use.

Storage Conditions

EE

Patents and Disclaimers

U.S. Pat. No. 9,139,868 and other patents pending.

U.S. Pat. No. 6,242,235, Australian Pat. No. 761757, Canadian Pat. No. 2,335,153 and other patents and patents pending.

U.S. Pat. No. 6,238,863 and other patents and patents pending.

Australian Pat. No. 724531, Canadian Pat. No. 2,251,793 and other patents and patents pending.

TMR-6C, CXR-6C, TOM-6C and WEN-6C dyes are proprietary.

Allele sequences for one or more of the loci vWA, FGA, D8S1179, D21S11 and D18S51 in allelic ladder mixtures is licensed under U.S. Pat. Nos. 7,087,380 and 7,645,580, Australia Pat. No. 2003200444 and corresponding patent claims outside the US.

Specifications

You are viewing: DC2720 Change Configuration

What's in the box?

Item Part # SizeConcentrationAvailable Separately

2800M Control DNA

DD710A 1 × 25μl10ng/μl View Product

PowerPlex® Fusion 6C Allelic Ladder Mix

DG417B 4 × 25μl

WEN Internal Lane Standard 500

DG500A 2 × 200μl View Product

PowerPlex® Fusion 6C 5X Primer Pair Mix

DK419B 4 × 250μl

PowerPlex® Fusion 6C 5X Master Mix

DP114A 4 × 250μl

Water, Amplification Grade

DW099A 5 × 1,250μl View Product

SDS

Choose language:

Certificate of Analysis

Search for Specific Certificate:

View more results
View more results
Loading…

Use Restrictions

Not For Medical Diagnostic Use.

Storage Conditions

EE

Patents and Disclaimers

U.S. Pat. No. 9,139,868 and other patents pending.

U.S. Pat. No. 6,242,235, Australian Pat. No. 761757, Canadian Pat. No. 2,335,153 and other patents and patents pending.

U.S. Pat. No. 6,238,863 and other patents and patents pending.

Australian Pat. No. 724531, Canadian Pat. No. 2,251,793 and other patents and patents pending.

TMR-6C, CXR-6C, TOM-6C and WEN-6C dyes are proprietary.

Allele sequences for one or more of the loci vWA, FGA, D8S1179, D21S11 and D18S51 in allelic ladder mixtures is licensed under U.S. Pat. Nos. 7,087,380 and 7,645,580, Australia Pat. No. 2003200444 and corresponding patent claims outside the US.

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