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Promega Corporation

ALK2 Kinase Enzyme System

See All Kinase Enzyme Systems
Recombinant human ALK2 (147–end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. ALK2 is a receptor serine/threonine kinase that is member of the ALK family and is upstream of signaling pathway involving the SMAD proteins especially SMAD1/5/8. Knockdown of ALK2, but not TGFβRI (ALK5), abrogates endoglin-mediated decrease in cell motility of prostate cancer cells, and constitutively active ALK2 is sufficient to restore a low-motility phenotype in endoglin-deficient cells (1). Therefore, endoglin decreases prostate cancer cell motility through activ...

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  • *Prices valid for US customers only
Product Size Conc. Catalog # *List Price QTY Add to Cart
ALK2 Kinase Enzyme System 10μg
- V4492 $ 435.00 Add to cart

ALK2 Kinase Enzyme System

- V6272 $ 6,399.00 Add to cart
ADP-Glo™ Kinase Assay + ALK2 Kinase Enzyme System 1 each
- V4493 $ 870.00 Add to cart

Storage Conditions

Upon receipt, centrifuge the kinase and dispense it into smaller quantities. Store the kinase at –70°C and the rest of the components at –20°C.

For product intended use please see Patents & Disclaimers tab.

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