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PMA

V1171_PMA-5mg

Phorbol 12-Myristate 13-Acetate

  • Specific activator of group A (α, βI, βII, γ) and group B (δ, ε, η, θ) Protein Kinase Cs
  • Supplied as a dried material

Size

Catalog number selected: V1171

$ 157.00
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PMA
5mg
$ 157.00
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Phorbol 12-myristate 13-acetate (PMA) is a specific activator of group A (α, βI, βII, γ) and group B (δ, ε, η, θ) Protein Kinase Cs (PKCs) (in the 1–100nM range). Phorbol esters, such as PMA, affect PKCs by mimicking diacylglycerol, a natural ligand and activator of PKCs. PMA is an effective skin irritant and potent tumor promoter in mice. A common alternative name for PMA is 12-O-tetradecanoylphorbol 13-acetate (TPA). The chemical identity and purity of PMA are confirmed by proton NMR.

Supplied as a dried material. Resuspend 5mg in 1.62ml of DMSO to produce a stock solution of 5mM.

Specifications

What's in the box?

Item Part # Size

PMA

V117A 1 × 5mg

SDS

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Download SDSPDF (45 KB) – English (United States)

Certificate of Analysis

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Use Restrictions

For Research Use Only. Not for Use in Diagnostic Procedures.

Storage Conditions

BB

Store dried material at –20°C.

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