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category-biologics

Functional Bioassays

Development of antibody-based therapeutics requires quantitative MOA-based bioassays during all stages of drug research and development. If your interests include antibody screening, characterization, potency and stability testing, explore our portfolio of assays.

21 Products


Application


Target Class


Target Pathway

Shop all Functional Bioassays

VEGF Blockade Bioassay

Measure potency and stability of biologics designed to block VEGF signaling.

TNFα Blockade Bioassay

Measure potency and stability of biologics designed to block TNFα interactions.

OX40 Bioassay

Measure potency and stability of biologics designed to be agonists of OX40.

4-1BB Bioassay

Measure potency and stability of biologics designed to be agonists of 4-1BB.

CD40 Bioassay

Measure potency and stability of biologics designed as agonists of the CD40 pathway.

GITR Activation Bioassay

Measure potency and stability of biologics designed to be agonists of GITR.

PD-1 + TIGIT Combination Bioassay

Measure the synergystic effects of anti-PD-1 and anti-TIGIT immune checkpoint blocking antibodies on T cell activation.

TIGIT/CD155 Blockade Bioassay

Measure potency and stability of biologics designed to block the TIGIT/CD155 interaction.

CTLA-4 Blockade Bioassay

Measure potency and stability of biologics designed to block CTLA-4 interaction.

PD-1/PD-L2 Blockade Bioassay

Measure potency and stability of biologics designed to block the PD-1/PD-L2 interaction with this custom assay.

T Cell Activation Bioassay

Assess T cell activation through TCR/CD3 complex engagement with the co-stimulatory receptor CD28.

J1621, J1625, J1651, J1655

Control Ab, Anti-PD-1

Anti-PD-1 blocking antibody for use with the PD-1/PD-L1 Blockade Bioassay.

J1201

Mouse ADCC Bioassays

Reporter assay to measure potency and stability of antibodies that bind and activate the mFcγRIV receptor.

M1201, M1211, M1215

PD-1/PD-L1 Blockade Bioassay

Immune checkpoint bioassays to characterize immune-modulating antibodies.

J1255, J1250

PD-L1 Negative Cells

One-time, ready-to-use control cells for PD-1/PD-L1 Blockade Bioassay.

J1191, J1195

Showing 21 of 21 Products

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