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category-biologics

Functional Bioassays

Development of antibody-based therapeutics requires quantitative MOA-based bioassays during all stages of drug research and development. If your interests include antibody screening, characterization, potency and stability testing, explore our portfolio of assays.

19 Products


Application


Target Class


Target Pathway

Shop all Functional Bioassays

GITR Bioassay

Measure potency and stability of biologics designed to be agonists of GITR.

VEGF Bioassay

A bioluminescent cell-based assay that measures VEGF stimulation and inhibition of KDR (VEGFR2).

GA2001, GA2005

4-1BB Bioassay

Measure potency and stability of biologics designed to be agonists of 4-1BB.

CD40 Bioassay

Measure potency and stability of biologics designed as agonists of the CD40 pathway.

OX40 Bioassay

Measure potency and stability of biologics designed to be agonists of OX40.

PD-1/PD-L2 Blockade Bioassay

Measure potency and stability of biologics designed to block the PD-1/PD-L2 interaction with this custom assay.

TNFα Blockade Bioassay

Measure potency and stability of biologics designed to block TNFα interactions.

PD-1+TIGIT Combination Bioassay

Measure the potency and stability of biologics designed to block immune checkpoint signals.

J2211, J2215

TIGIT/CD155 Blockade Bioassay

Measure the potency and stability of biologics designed to block the interaction of TIGIT and CD155

J2201, J2205

CTLA-4 Blockade Bioassay

Measure potency and stability of biologics designed to block CTLA-4 interaction.

JA3001, JA3005

Mouse ADCC Bioassays

Reporter assay to measure potency and stability of antibodies that bind and activate the mFcγRIV receptor.

M1201, M1211, M1215

T Cell Activation Bioassay

Assess T cell activation through TCR/CD3 complex engagement with the co-stimulatory receptor CD28.

J1621, J1625, J1651, J1655

PD-1/PD-L1 Blockade Bioassay

Immune checkpoint bioassays to characterize immune-modulating antibodies.

J1255, J1250

Bio-Glo™ Luciferase Assay System

Stable luciferase reagent ideal for reporter bioassays.

G7940, G7941

ADCP Bioassays

Reporter assay to measure potency and stability of antibodies that bind and activate FcγRIIa-H.

G9901, G9991, G9995

Showing 19 of 19 Products