CD1D, CD1d molecule

CD1D, CD1d molecule

• This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]

• Gene Synonyms (antigen-presenting glycoprotein CD1d, CD1D antigen, d polypeptide, HMC class I antigen-like glycoprotein CD1D, T-cell surface glycoprotein CD1d, differentiation antigen CD1-alpha-3, thymocyte antigen CD1D, CD1A, R3, R3G1,)
• NCBI Gene ID: 912
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P15813
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

CD1d molecule interacts with:

• CD74 molecule
  prolyl 4-hydroxylase subunit beta
  prolyl 4-hydroxylase, transmembrane
  protein tyrosine phosphatase receptor type C

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.