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Promega Corporation

Promega Expands "Glo" Reporter Technology Beyond Firefly Luciferase

MADISON, WISCONSIN (December 22, 2010)

The new Renilla-Glo™ Luciferase Assay brings the convenience of the "add, mix, measure" assay format to applications using the sea pansy (Renilla reniformis) luciferase. The assay is ideal for screening in applications where a smaller molecular size reporter gene, compared to the typical firefly luciferase, is desirable. The extended signal half-life and low background formulation support its use in high-density plate formats common to many screening programs.

While Renilla luciferase has widespread use as a normalization tool in the Dual-Luciferase® Assay, this unique luciferase is increasingly used as a single or primary reporter in applications such as transcription regulation, cell signaling and antiviral drug screening. Assay precision is improved as there is no need for separate lysis and reagent injection steps.

The Renilla-Glo Luciferase Assay approach – with substrate and buffer optimized and ready to use – expands the small but popular Renilla luciferase reporter gene to the suite of easy-to-use reporter assay technology systems.

About Promega

Promega Corporation is a leader in providing innovative solutions and technical support to the life sciences industry. The company's 2,000 products enable scientists worldwide to advance their knowledge in genomics, proteomics, cellular analysis, molecular diagnostics and human identification. Founded in 1978, the company is headquartered in Madison, WI, USA with branches in 14 countries and over 50 global distributors. For more information about Promega, visit www.promega.com.

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