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A Bright New Approach Promega’s range of ADME systems are designed to harness the power of bioluminescence to bring you assays that are not influenced by cellular or compound autofluorescence or excitation photon interference. As a result our bioluminescent solutions offer greater sensitivity (up to 4 logs) compared to fluorescent methods. |
ADME Screening Early in Drug Discovery
The ability to determine the ADME properties of new chemical entities
early in the drug discovery process would reduce late stage
failures,
saving time and money, and aid better drug design.
Promega offers
cell-based and enzyme assays which would enable biologically relevant data
to be collected early in the discovery process. Systems are available
for:
Cytochrome P450s
| P-glycoprotein (Pgp)
| Monoamine oxidase (MAO)
| Request More
Information
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Why switch to
Bioluminescence? When viewed on a log
scale the difference in how the excited state is created
translates up to 4 logs greater sensitivity for bioluminescence
relative to fluorescence. |
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the simplest way to directly access reagents in your lab.
Contact the UK office
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