Transfection Calculator - Introduction

The Transfection Reagent Calculator calculates the amount of DNA, transfection reagent and medium needed for preparation of transfection reagent/DNA master mix to be used in transfection experiments.

Select transfection reagent, type of vessel (tissue culture plate or dish), desired final volume, desired amount of DNA per well or dish, DNA concentration (if desired), reagent to DNA charge ratio, and number of replicates (wells or dishes) from the menu choices. Once the plate or dish size is selected, the volume field automatically updates to display the recommended volume for each well or dish; this field can be changed from this default value. We recommend 0.5ml of total volume per 1 × 106 suspension cells. Please set the volume per transfection accordingly if you are using suspension cells.

It is essential to optimize specific transfection conditions to gain optimal transfection efficiencies. For detailed information on optimizing transfection conditions and transfection experimental procedures, please see the Tfx™-10, Tfx™-20 and Tfx™-50 Reagents for the Transfection of Eukaryotic Cells Technical Bulletin #TB216 and Transfast™ Transfection Reagent Technical Bulletin #TB260.

Proceed to use the Transfection Calculator