Abstract for pGL2 Luciferase Reporter Vectors

Part# TM003
Printed in USA. Revised 2/09.
Instructions for Use of Products E1611, E1621, E1631 and E1641

Abstract for pGL2 Luciferase Reporter Vectors

The pGL2 Luciferase Reporter Vectors provide a basis for the quantitative analysis of factors that potentially regulate mammalian gene expression. These factors may be cis-acting, such as promoters and enhancers, or trans-acting, such as various DNA-binding factors. The pGL2 Vectors carry the coding region for firefly (Photinus pyralis) luciferase, used to monitor transcriptional activity in transfected eukaryotic cells. The assay of this genetic reporter is rapid, sensitive and quantitative. In addition, the pGL2 Vectors contain numerous features that aid the characterization and mutagenesis of the putative regulatory sequences.