Abstract for GloResponse™ NF-κB-RE-luc2P HEK293 Cell Line

Part# TB380
Printed in USA. Revised 2/09.
Instructions for Use of Product E8520.

The GloResponse™ NF-κB-RE-luc2P HEK293 Cell Line is a clonal derivative of Human Embryonic Kidney 293 (HEK293) cells. These cells contain a luciferase gene (luc2P) under the control of a minimal TATA promoter with multiple Nuclear Factor-κB response elements (NF-κB-REs). NF-κB-REs are the DNA binding sequences for the NF-κB transcription factor, which is responsible for regulating inflammation, immune response, cell growth and apoptosis. The GloResponse™ NF-κB-RE-luc2P HEK293 Cell Line is designed for rapid and convenient analysis of any cellular response that results in modulation of NF-κB activities.