Abstract for GloResponse™ NFAT-RE-luc2P HEK293 Cell Line

Part# TB363
Printed in USA. Revised 2/09.
Instructions for Use of Product E8510.

The GloResponse™ NFAT-RE-luc2P HEK293 Cell Line is a clonal derivative of Human Embryonic Kidney 293 (HEK293) cells. These cells contain a luciferase gene (luc2P) under the control of a minimal TATA promoter with multiple Nuclear Factor of Activated T-cell response elements (NFAT-REs). NFAT-REs are the DNA binding sequences for the NFAT family of transcription factors, which are responsible for regulating a variety of biological functions including cell proliferation, cytokine production, and cardiovascular development. The GloResponse™ NFAT-RE-luc2P HEK293 Cell Line is designed for rapid and convenient analysis of any cellular response that results in modulation of NFAT activities.