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Abstract for GloResponse™ CRE-luc2P HEK293 Cell Line
The GloResponse™ CRE-luc2P HEK293 Cell Line is a clonal
derivative of Human Embryonic Kidney 293 cells that contain a
luciferase gene (luc2P) under the control of a minimal Herpes
Simplex Virus (HSV) thymidine kinase promoter with multiple cAMP
Response Elements (CREs). CRE is the DNA binding sequence for the
transcription factor CRE binding protein (CREB), which is
responsible for the regulation of a variety of biological functions
including cell proliferation, circadian rhythms and memory. The
GloResponse™ CRE-luc2P HEK293 Cell Line is designed for rapid and
convenient analysis of any cellular response that results in
modulation of CREB activities.
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