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Abstract for Anti-ACTIVE® MAPK, p38 and JNK Polyclonal Antibodies and
Anti-ACTIVE® Qualified Secondary Antibody Conjugates
Promega has developed polyclonal antibodies (pAb) to three members of the
Mitogen-Activated Protein Kinase (MAPK) superfamily of enzymes. These enzymes,
which play important roles in signal transduction in eukaryotic cells, are MAPK,
p38 and JNK. These kinases have interconnected roles in a cascade of signal
transduction reactions. The Anti-ACTIVE® pAbs are specific for the
dually phosphorylated active forms of MAPK, p38 and JNK and provide a tool for
more accurate measurement of activation of these enzymes.
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