Abstract for Anti-ACTIVE^® MAPK, p38 and JNK Polyclonal Antibodies and Anti-ACTIVE^® Qualified Secondary Antibody Conjugates

Part# TB262
Printed in USA. Revised 3/09.
Instructions for Use of Products V1211, V8031, V7931, V7932, V7951, V7971 & V3281.

Promega has developed polyclonal antibodies (pAb) to three members of the Mitogen-Activated Protein Kinase (MAPK) superfamily of enzymes. These enzymes, which play important roles in signal transduction in eukaryotic cells, are MAPK, p38 and JNK. These kinases have interconnected roles in a cascade of signal transduction reactions. The Anti-ACTIVE^® pAbs are specific for the dually phosphorylated active forms of MAPK, p38 and JNK and provide a tool to measure more accurately activation of these enzymes.