|
Download
protocol
59kb
pdf? |
|
Abstract for Anti-ACTIVE® Caspase-3 pAb
Anti-ACTIVE® Caspase-3 pAb is intended for use as a
marker of apoptosis; it specifically stains apoptotic human cells without
staining nonapoptotic cells. Cysteine proteases called caspases are among the
mediators of the execution phase of apoptosis. Caspase-3 is a central player in
mediating apoptosis and is the most widely studied caspase. All known caspases
are synthesized as proenzymes activated by proteolytic cleavage. Anti-ACTIVE®
Caspase-3 pAb is an affinity-purified rabbit polyclonal antibody directed
against a peptide from the p18 fragment of human caspase-3. The antibody is
affinity purified using a peptide corresponding to the cleaved region of
caspase-3.
|
