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Abstract for Automated Multiplexed Cell-Based Assays for
High-Throughput Drug Discovery
Brad Larson1, Tracy Worzella1, Siegfried Sasshofer2, Aoife
Gallagher3
1Promega Corporation, Madison, WI, 2Tecan Austria GmbH, , 3Deerac
Fluidics, Dublin, Ireland
To meet demands for measuring multiple parameters from a single
sample, we demonstrate the utility of Promega cell-based assays,
including reporter assays, in multiplex experiments. Here we
provide proof-of-principle data by combining Promega's cell-based
screening assays in a multiplexed format with a variety of
high-throughput liquid handling and detection instrumentation. The
data show the ability to combine assay chemistries with laboratory
instrumentation, in a high-throughput setting, in order to obtain
more information from one sample well.
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