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Promega Webinars

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Welcome to the Promega Webinar Series, an ongoing communication designed to keep you informed. Learn about basic concepts, tips and techniques to help your research, or understand how products were designed and how to implement in your lab. All presentations will be given by Promega scientists and you will have an opportunity to interact with our Technical Service Scientist directly during live events via chat. The webinars are free though we do ask that you register for the events. Registration allows us to send you the URL for the webinar.

Factors to Consider for Designing and Optimizing Assays Applied to 3D Cultures

Cell-Based Assays

Tuesday, September 13, 2016

Terry Riss, PhD

3D cell culture models present a challenge for using assay chemistries and imaging methods that were originally designed for measuring events from 2D monolayers of cells. In this webinar, we will present factors to consider when designing and optimizing assays applied to 3D cell culture models, case studies describing design of reagents to overcome the limitations inherent with detecting markers from large 3D culture models, and applications of novel real-time detection methods.

Immune Checkpoint Bioassays Power Combination Immunotherapy

Drug Discovery

Tuesday, September 27, 2016

Richard Somberg, PhD

Therapeutic antibodies designed to block or activate immune checkpoint receptors are a powerful new approach to the treatment of cancer and other diseases. However, due to their biologic complexity the development of therapeutic antibodies requires unique functional and analytical tools. Here we present a suite of MOA-based functional bioassays for use in antibody screening, characterization, potency testing and stability studies.

Faster Mass Spec: Same-Day Sample Prep Now a Reality

Proteomics

Tuesday, October 25, 2016

Micheal M. Rosenblatt, PhD

Traditional protocols require digestion times of up to 18 hours, as well as reduction and alkylation prior to digestion. These denaturants often inhibit enzymes and modify proteins, and require removal prior to analysis. What if you could shorten digestion times to ~30 minutes, without denaturants or reductants or alkylating agents?

Did you miss one of our webinars? Simply select the appropriate link below and view the recorded webinar. It will not be interactive, but you will see the chat questions the original attendees asked. For additional information on the products discussed in the webinar, explore our links to videos and other resources.

If there is an area you would like to see covered, you can request a topic of your choice.

If you are experiencing issues opening the webinar recordings, please be sure that you have the latest Adobe Flash Player installed.

Bioactivity Assays: Putting the Puzzle Together

Drug Discovery

Tuesday, April 12, 2016

Ulrike Herbrand, PhD, Charles River Laboratories

In past years, the requirement for bioactivity testing changed from later phase lot release and stability testing to additional applications like biocomparability testing for follow-on biologics, accelerated stress condition testing and confirmation of successful production scale up. Therefore a suitable bioassay is needed at a very early time point. This webinar will look at a wide variety of therapeutic proteins and illustrate some best practices in method development that results in reliable, reproducible and precise assays, and discuss which assays may be best for your product and development program.

Isolation of Circulating Tumor DNA from Archived Plasma Samples for Downstream Digital Droplet PCR and Next Generation Sequencing Approaches

Genomics

Tuesday, March 22, 2016

Andrew Benjamin Nixon, PhD, MBA, Duke University School of Medicine

This webinar will explore circulating cell-free DNA workflows for biomarker discovery and downstream NGS analysis of tumor samples in a research environment.

Understanding Luminescent Reporter Assay Design

Cell-Based Assays

Tuesday, March 08, 2016

Carl Strayer, PhD

Luminescent reporter assays are powerful research tools for a variety of applications. This webinar explains critical aspects of reporter assay design to help you implement a robust assay that delivers meaningful results.

Maintaining Scientific Integrity Through Cell Line Authentication

Genomics

Tuesday, January 26, 2016

Gabriela Saldanha & Martin Ensenberger, PhD

Human cell line misidentification is a common problem in the research community that can have significant negative consequences. As of January 2016, applicants for grants will be required to authenticate key biological resources, including cell lines. This webinar will provide a brief history of cell line contamination and outline a simple and inexpensive method for authenticating human cell lines.

Understanding the Role of the Inflammasome in Inflammation

Cell-Based Assays

Tuesday, January 12, 2016

Martha O'Brien, PhD

This webinar will discuss two important outcomes of inflammasome induction, caspase-1 activation and pyroptosis, and will present a new method for directly measuring caspase-1 activation.

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