Similar biological characteristics of human embryonic stem cell lines with normal and abnormal karyotypes.
Sun, X., Long, X., Yin, Y., Jiang, Y., Chen, X., Liu, W., Zhang, W., Du, H., Li, S., Zheng, Y., Kong, S., Pang, Q., Shi, Y., Huang, Y., Huang, S., Liao, B., Xiao, G. and Wang, W.
Notes: The authors developed seven new human embryonic stem cell (hESC) lines, five with normal karyotypes and two with abnormal karyotypes. They examined their biological characteristics, STR loci, HLA typing, differentiation capability, imprinted genes, DNA methylation and X chromosome inactivation status to determine if hESC lines with abnormal karyotypes are useful experimental tools. STR genotyping was performed using the PowerPlex® 16 System and the ABI PRISM® 3100 Genetic Analyzer. (4040)
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