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Am. J. Kidney Dis. 34, 328-337. Sodium bicarbonate treatment reduces renal injury, renal production of transforming growth factor-beta, and urinary transforming growth factor beta excretion in rats with doxorubicin-induced nephropathy 1999

Baroni, E.A., Costa, R.S., Volpini, R. and Coimbra, T.M.

Notes: The TGFβ1 Emax® ImmunoAssay System was used to measure TGFβ1 levels in the urine of control and doxorubicin-treated rats. The urine was acidified to measure total TGFβ1 by the ELISA and the results are reported as picograms of TGFβ1 per milligram of creatine to correct for variation in urine concentration. (1462)

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J. Immunol. 162, 4122-4132. Tolerization of mice to Schistosoma mansoni egg antigens causes elevated type 1 and diminished type 2 cytokine responses and increased mortality in acute infection. 1999

Fallon, P.G., and Dunne, D.W.

Notes: The TGFβ1 EMAX® ImmunoAssay System was used to determine the amount of TGFβ1 secreted from granuloma cells isolated from mouse livers. (TGFβ1 ELISA) (1192)

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J. Immunol. 160, 5314-5319. 1,25-dihydroxyvitamin D3 is a positive regulator for the two anti-encephalitogenic cytokines TGF-beta 1 and IL-4. 1998

Cantorna, M. T. , Woodward, W. D. , Hayes, C. E. , DeLuca, H. F.

Notes: The TGF Beta1 Emax® ImmunoAssay System (TGFbeta1 ELISA) was used to measure levels of TGF Beta1 in the lymph nodes and peritoneal cells of control and 1,25-dihydroxyvitamin D3 treated mice. (1386)

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Am. J. Respir. Cell Mol. Biol. 18, 823-833. Angiotensin II induces hypertrophy of human airway smooth muscle cells: expression of transcription factors and transforming growth factor-beta1. 1998

McKay, S., de Jongste, J.C., Saxena, P.R., Sharma, H.S.

Notes: The TGFbeta1 Emax® ImmunoAssay System was used to quantitate TGFβ1 from human aortic smooth muscle cells. (0711)

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J. Immunol. 160, 2523-2530. Malaria elicits type 1 cytokines in the human placenta: IFN-gamma and TNF-alpha associated with pregnancy outcomes. 1998

Fried, M., Muga, R.O., Misore, A.O., Duffy, P.E.

Notes: The TGFβ1 Emax® ImmunoAssay System was used to determine the level of TGFβ1 in the placental sera of Kenyan women who were either exposed or unexposed to malaria. Those unexposed (~100pg/ml) to malaria had approximately 5-fold less TGFβ1 as those exposed (~500pg/ml). (1123)

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J. Neurosci. 18, 9594-9600. Neuroprotection by glial metabotropic glutamate receptors in mediated by transforming growth factor-beta 1998

Bruno, V., Battaglia, G., Casabona, G., Copani, A., Caciagli, F. and Nicoletti, F.

Notes: The TGFβ1 Emax® ImmunoAssay System was used to confirm TGFβ1 levels in cultured mouse astrocytes conditioned media. The first screen for TGFβ1 was the mink lung epithelial cell bioassay. The control astrocyte media contained 6.4pg/ml and glutamate receptor agonist-treated astrocyte media contained 38pg/ml. (2243)

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J. Immunol. 161, 6297-6304. Oral Delivery of group A streptococcal cell walls augments circulating TGF-beta and suppresses streptococcal cell wall arthritis 1998

Chen, W., Jin, W., Cook, M., Weiner, H.L., Wahl, S.M.

Notes: TGFbeta1 levels were measured in serum from LEW female rats following oral delivery of group A streptococcal cell walls. The serum was diluted 1:30 prior to assay for active TGFbeta1 and acid-activated to measure total TGFbeta1. The level of TGFbeta1 was also assessed in primary spleen cultures and mucosal lymphoid tissue conditioned media before and after challenge with the cell walls. Quantitation of the growth factor was performed with the TGFbeta1 Emax® ImmunoAssay System. (TGFbeta1 ELISA) (1329)

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Am. J. Physiol. 274, G1068-G1076. Regulation of endothelin synthesis in hepatic endothelial cells. 1998

Eakes, A.T. , Olson, M.S.

Notes: Authors used the TGF-β1 Emax® ImmunoAssay System (TGFβ1 ELISA) with rat kupffer and liver endothelial cells. (1212)

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Blood 89, 941-947. Chronic lymphocytic leukemia B cells are resistant to the apoptotic effects of transforming growth factor-beta. 1997

Douglas, R. S. , Capocasale, R. J. , Lamb, R. J. , Nowell, P. C. , Moore, J. S.

Notes: The TGFbeta1 Emax® ImmunoAssay System (TGFb1 ELISA) was used to quantitate the amount of active and latent TGF-beta1 produced by chronic lymphocytic leukemia (CLL) B cells and normal CD19+ B cells in culture. The CLL B cells produced a total of 233pg/ml with 18% active and normal B cells produced 186pg/ml with 4% active. (1246)

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J. Biol. Chem. 272, 12862-12867. Expression of transforming growth factor beta (TGFbeta) type III receptor restores autocrine TGFbeta1 activity in human breast cancer MCF-7 cells. 1997

Chen, C. , Wang, X. F. , Sun, L.

Notes: The TGFbeta1 Emax® ImmunoAssay System was used to monitor TGFbeta1 secreted into conditioned media by a TGFbeta Type III receptor-transfected MCF-7 human breast cancer cells. (TGFbeta1 ELISA) (1366)

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J. Biol. Chem. 272, 25367-25372. Expression of transforming growth factor beta type III receptor suppresses tumorigenicity of human breast cancer MDA-MB-231 cells. 1997

Sun, L. and Chen, C.

Notes: The TGFβ1 Emax® ImmunoAssay System was used to monitor TGFβ1 in conditioned media from cells transfected with the TGFβ type III receptor or cells transfected with vector alone. The mock-transfected cells produced 49pg/106 cells/72 hours and the receptor expressing cells had levels below the detection limit of the assay. (1544)

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J. Clin. Invest. 98, 70-77. Induction of circulating myelin basic protein and proteolipid protein-specific transforming growth factor-beta1-secreting Th3 T cells by oral administration of myelin in multiple sclerosis patients. 1997

Fukaura, H., Kent, S.C., Pietrusewicz, M.J., Khoury, S.J., Weiner, H.L. and Hafler, D.A.

Notes: The TGF-beta1 Emax ImmunoAssay System was used to measure TGF-beta1 in T cell culture supernatants stimulated with different antigens. (1572)

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J. Exp. Med. 184, 2167-2174. Aerosol insulin induces regulatory CD8 gamma delta T cells that prevent murine insulin-dependent diabetes. 1996

Harrison, L.C., Dempsey-Collier, M., Kramer, D.R. and Takahashi, K.

Notes: The TGF-beta1 Emax ImmunoAssay System was used to monitor TGF-beta1 expression of aerosol treated mouse splenocytes culture supernatants in response to insulin B chain peptide. (1577)

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J. Clin. Invest. 98, 2496-2506. Intracellular demonstration of active TGFbeta1 in B cells and plasma cells of autoimmune mice. IgG-bound TGFbeta1 suppresses neutrophil function and host defense against Staphylococcus aureus infection. 1996

Caver, T.E., O’Sullivan, F.X., Gold, L.I. and Gresham, H.D.

Notes: The TGF-beta1 Emax ImmunoAssay System system was used to measure TGF-beta1 levels in plasma and peritoneal lavage samples of mice. (1611)

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