We believe this site might serve you best:

United States

English Continue

This country code will remain if no action is taken to change it.

Don't see your country?
Promega Corporation

Rat Hepatocyte Culture Physiology Shows Enhanced Cytochrome P450 Activity on a...

Rat Hepatocyte Culture Physiology Shows Enhanced Cytochrome P450 Activity on a Synthetic Extracellular Matrix
  • Print
  • Email
  • Download PDF


We examined the impact of a new three-dimensional synthetic matrix on hepatocyte physiology. Hepatocytes were plated on Corning labware with Ultra-Web™ and Ultra-Web™ polyamine surfaces and on Becton Dickinson (BD) BioCoat™ collagen I microplates. The samples then were challenged for 48 hours with two known modulators of cytochrome P450, and P450 activity was measured using the P450-Glo® Assay. The data show enhanced physiologic function of primary rat hepatocytes on microplates coated with the Ultra-Web™ synthetic matrix.

Promega Notes 99, 29–31.

Mark E. Rothenberg1, James J. Cali2, Mary Sobol2, Michael W. Briggs1 and Todd Upton1

1Technical Applications, Corning Life Sciences, 2Promega Corporation
Publication Date: 2008

Download Article (200 KB)

It appears that you have Javascript disabled. Our website requires Javascript to function correctly. For the best browsing experience, please enable Javascript.

Scientists at Your Service

Scientists at Your Service

We offer a range of services to help you succeed using Promega technologies. From product training to set up of automated systems and development of custom applications—our scientific support goes beyond the basics.

Ask us! We are here to help you.