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Promega Corporation

The Y Chromosome Deletion Detection System, Version 1.1

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Abstract

The identification and analysis of pathology associated with Y chromosome deletions is an important tool for the study of male infertility. Screening for Y chromosome deletions has been hampered by a lack of standardized primer sets for sequence tagged sites (STSs). The Y Chromosome Deletion Detection System, Version 1.1, offers the opportunity for standardization using four Multiplex Master Mixes that screen for a total of eighteen previously identified and mapped STSs. Y chromosome deletions in the regions amplified by these primers are associated with male infertility.

Promega Notes 74, 14–17.

Susan Frackman, Marijo Kent, and Angela Ryan

Promega Corporation

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