In Vitro Compound Profiling in 384- and 1536-Well Formats Using Bioluminescent ADME...

This article describes metabolic profiling applications in which compounds are assayed against several different drug metabolizing enzymes on the same assay plate. We obtain potency data for cytochrome P450 and monoamine oxidase A using this parallel approach and dose-response testing of compounds using both 384-well and 1536-well plate configurations.

Cell Notes 16, 4–8.